BDBM50189909 CHEMBL3827363

SMILES Nc1ccc(cc1NC(=O)C1COc2ccccc2C1)-c1ccc(F)cc1

InChI Key InChIKey=XUSNOOWXXNLURK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50189909   

TargetHistone deacetylase 3(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM50189909(CHEMBL3827363)
Affinity DataIC50: >3.33E+4nMAssay Description:Inhibition full length human recombinant HDAC3 expressed in baculovirus using carboxyfluorescein (FAM)-labeled acetylated/ trifluoroacetylated peptid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM50189909(CHEMBL3827363)
Affinity DataIC50:  156nMAssay Description:Inhibition full length human recombinant HDAC2 expressed in baculovirus coexpressed in fall armyworm Sf9 cells using carboxyfluorescein (FAM)-labeled...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM50189909(CHEMBL3827363)
Affinity DataIC50:  72nMAssay Description:Inhibition of C-terminal His-tagged and C-terminal FLAG-tagged full length human recombinant HDAC1 expressed in baculovirus coexpressed in fall armyw...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed