BDBM50189930 CHEMBL3828475::US10618914, Compound 8b::US11111253, Compound 8b

SMILES COc1ccc(cc1)C1=Nn2c(SC1)nnc2-c1cc(n[nH]1)-c1ccccc1

InChI Key InChIKey=MQDVTXABMFOTPZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50189930   

TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50189930(CHEMBL3828475 | US10618914, Compound 8b | US111112...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of IL6-induced STAT3 in human CAL33 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 1-alpha/beta(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50189930(CHEMBL3828475 | US10618914, Compound 8b | US111112...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of IFNgamma-induced STAT1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 1-alpha/beta(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50189930(CHEMBL3828475 | US10618914, Compound 8b | US111112...)
Affinity DataIC50: >5.00E+4nMAssay Description:Compound samples (in 3-5 mg quantities) were evaluated in a variety of assays. All compound submissions were fully characterized (1H, 13C, IR, FIRMS)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSignal transducer and activator of transcription 1-alpha/beta(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50189930(CHEMBL3828475 | US10618914, Compound 8b | US111112...)
Affinity DataIC50:  4.06E+4nMAssay Description:Compound samples (in 3-5 mg quantities) were evaluated in a variety of assays. All compound submissions were fully characterized (1H, 13C, IR, HRMS),...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50189930(CHEMBL3828475 | US10618914, Compound 8b | US111112...)
Affinity DataIC50:  1.79E+4nMAssay Description:Compound samples (in 3-5 mg quantities) were evaluated in a variety of assays. All compound submissions were fully characterized (1H, 13C, IR, FIRMS)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50189930(CHEMBL3828475 | US10618914, Compound 8b | US111112...)
Affinity DataIC50:  1.79E+4nMAssay Description:Compound samples (in 3-5 mg quantities) were evaluated in a variety of assays. All compound submissions were fully characterized (1H, 13C, IR, HRMS),...More data for this Ligand-Target Pair
In DepthDetails US Patent