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BDBM50190171 CHEMBL3827219

SMILES: Cc1nc2ccccc2n1CC(=O)NNC(=O)Cc1ccccc1C

InChI Key: InChIKey=IOWSECSAESTKNP-UHFFFAOYSA-N

Data: 1 IC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50190171   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (human))
BDBM50190171
PNG
(CHEMBL3827219)
Show SMILES Cc1nc2ccccc2n1CC(=O)NNC(=O)Cc1ccccc1C
Show InChI InChI=1S/C19H20N4O2/c1-13-7-3-4-8-15(13)11-18(24)21-22-19(25)12-23-14(2)20-16-9-5-6-10-17(16)23/h3-10H,11-12H2,1-2H3,(H,21,24)(H,22,25)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 92n/an/an/an/an/an/a



Jamia Hamdard (Hamdard University)

Curated by ChEMBL


Assay Description
Inhibition of recombinant human N-terminal His-tagged GSK-3beta expressed in Escherichia coli using glycogen synthase-2 as substrate and ATP measured...


Bioorg Med Chem Lett 26: 4020-4 (2016)


Article DOI: 10.1016/j.bmcl.2016.06.084
BindingDB Entry DOI: 10.7270/Q2639RP0
More data for this
Ligand-Target Pair