BDBM50190328 CHEMBL3827342

SMILES CCc1ccc(cc1)N1C(=S)N(C)\C(=C/c2ccc(cc2)N(C)C)C1=O

InChI Key InChIKey=FEQBFJABEFHTOQ-RGEXLXHISA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50190328   

TargetNADPH oxidase 4(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190328(CHEMBL3827342)
Affinity DataKi:  2.63E+3nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNADPH oxidase 1(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50190328(CHEMBL3827342)
Affinity DataKi:  4.39E+3nMAssay Description:Inhibition of human NOX1 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed