BDBM50190362 1-{3-[4-(tert-butyl) phenyl]-5-N,N-dimethylaminomethyl-(1,2,4-triazol-4-yl)}-3-phenol::3-(3-(4-tert-butylphenyl)-5-((dimethylamino)methyl)-4H-1,2,4-triazol-4-yl)phenol::CHEMBL212375

SMILES CN(C)Cc1nnc(-c2ccc(cc2)C(C)(C)C)n1-c1cccc(O)c1

InChI Key InChIKey=VARCIQVXDHUYNT-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50190362   

TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Medicine And Dentistry Of New Jersey And Umdnj Informatics Institute

Curated by ChEMBL
LigandPNGBDBM50190362(1-{3-[4-(tert-butyl) phenyl]-5-N,N-dimethylaminome...)
Affinity DataKi:  460nMAssay Description:Inhibition of (-)-[9-3H]bremazocine binding to delta opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Medicine And Dentistry Of New Jersey-Robert Wood Johnson Medical School And The Informatics Institute Of Umdnj

Curated by ChEMBL
LigandPNGBDBM50190362(1-{3-[4-(tert-butyl) phenyl]-5-N,N-dimethylaminome...)
Affinity DataKi:  460nMAssay Description:Displacement of [3H]bremazocine from mouse delta opioid receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Medicine And Dentistry Of New Jersey And Umdnj Informatics Institute

Curated by ChEMBL
LigandPNGBDBM50190362(1-{3-[4-(tert-butyl) phenyl]-5-N,N-dimethylaminome...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of (-)-[9-3H]bremazocine binding to kappa opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Medicine And Dentistry Of New Jersey And Umdnj Informatics Institute

Curated by ChEMBL
LigandPNGBDBM50190362(1-{3-[4-(tert-butyl) phenyl]-5-N,N-dimethylaminome...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of (-)-[9-3H]bremazocine binding to mu opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University Of Medicine And Dentistry Of New Jersey-Robert Wood Johnson Medical School And The Informatics Institute Of Umdnj

Curated by ChEMBL
LigandPNGBDBM50190362(1-{3-[4-(tert-butyl) phenyl]-5-N,N-dimethylaminome...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]bremazocine from rat kappa opioid receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
University Of Medicine And Dentistry Of New Jersey-Robert Wood Johnson Medical School And The Informatics Institute Of Umdnj

Curated by ChEMBL
LigandPNGBDBM50190362(1-{3-[4-(tert-butyl) phenyl]-5-N,N-dimethylaminome...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]bremazocine from mouse mu opioid receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed