BDBM50190466 CHEMBL212431::N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-{4-[4-(3-hydroxypropoxy)phenyl]-butyl}guanidine

SMILES NC(NC(=O)c1nc(Cl)c(N)nc1N)=NCCCCc1ccc(OCCCO)cc1

InChI Key InChIKey=UWTBBJUQVGVXNE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50190466   

TargetAmiloride-sensitive sodium channel subunit alpha(Homo sapiens (Human))
Parion Sciences

Curated by ChEMBL
LigandPNGBDBM50190466(CHEMBL212431 | N-(3,5-diamino-6-chloropyrazine-2-c...)
Affinity DataIC50:  7nMAssay Description:Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed