BDBM50190551 1-[2-(tert-butyldimethylsilyloxyethoxy)methyl]uracil::CHEMBL213682

SMILES CC(C)(C)[Si](C)(C)OCCOCn1ccc(=O)[nH]c1=O

InChI Key InChIKey=STXDHUSBXJTEGB-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50190551   

TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase(Plasmodium falciparum)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50190551(1-[2-(tert-butyldimethylsilyloxyethoxy)methyl]urac...)
Affinity DataKi:  4.40E+4nMAssay Description:Inhibition of Plasmodium falciparum dUTPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50190551(1-[2-(tert-butyldimethylsilyloxyethoxy)methyl]urac...)
Affinity DataKi:  6.30E+4nMAssay Description:Inhibition of human recombinant dUTPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50190551(1-[2-(tert-butyldimethylsilyloxyethoxy)methyl]urac...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of human dUTPase assessed as production of [5-3H]dUMP from [5-3H]dUTP after 15 mins measured by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed