BDBM50191632 CHEMBL209262::rac-N-ethyl-N-[3-(5-fluoro-1H-indol-3-yl)propyl]-5-methoxychroman-3-amine

SMILES CCN(CCCc1c[nH]c2ccc(F)cc12)C1COc2cccc(OC)c2C1

InChI Key InChIKey=RMGYTGHXLUNSGI-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50191632   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191632(CHEMBL209262 | rac-N-ethyl-N-[3-(5-fluoro-1H-indol...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]paroxetine from 5-HT transporter in Sprague-Dawley rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191632(CHEMBL209262 | rac-N-ethyl-N-[3-(5-fluoro-1H-indol...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191632(CHEMBL209262 | rac-N-ethyl-N-[3-(5-fluoro-1H-indol...)
Affinity DataIC50:  64nMAssay Description:Inhibition of [3H]5-HT uptake at human 5-HT transporter expressed in Jar cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed