BDBM50192779 CHEMBL3957347

SMILES [H][C@]12CC[C@]([H])(C\C(C1)=N/OC[C@@H](O)C(F)(F)F)N2C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1

InChI Key InChIKey=ITKLIKLCPRZARE-VQWDRWJBSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50192779   

TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL

LigandBDBM50192779(CHEMBL3957347)Copy SMILESCopy InChI

Affinity DataIC50:  1.10nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
Shionogi

Curated by ChEMBL

LigandBDBM50192779(CHEMBL3957347)Copy SMILESCopy InChI

Affinity DataIC50:  29nMAssay Description:Antagonist activity at rat TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI