BDBM50192803 CHEMBL3906685

SMILES CO[C@@H]1C[C@@H]2CC[C@H](C1)N2C(=O)c1ccc(Nc2nc(cs2)-c2sc(C)nc2C)nc1

InChI Key InChIKey=NIRLMVVCSRWKLO-FVQHAEBGSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50192803   

TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50192803(CHEMBL3906685)
Affinity DataIC50:  2.40nMAssay Description:Antagonist activity at human TRPV4 assessed as inhibition of 4alpha-PDD-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed