BDBM50192829 CHEMBL3958704::US10188627, Compound 8a
SMILES CN(Cc1ccccc1OC\C=C(/C)CCC(O)=O)C(=O)c1ccc(cc1)-c1ccco1
InChI Key InChIKey=WZFMWAHUFRLQRH-XDJHFCHBSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 19 hits for monomerid = 50192829
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Temple University
Curated by ChEMBL
Temple University
Curated by ChEMBL
Affinity DataEC50: 56nMAssay Description:Transactivation of human Gal4-PPARdelta LBD transfected in African green monkey CV1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Mitobridge
Curated by ChEMBL
Mitobridge
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Modulator activity at GAL4-fused human PPARgamma LBD (unknown origin) transfected in African green monkey CV1 cells assessed as receptor transactivat...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Temple University
Curated by ChEMBL
Temple University
Curated by ChEMBL
Affinity DataEC50: 5.06nMAssay Description:Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Temple University
Curated by ChEMBL
Temple University
Curated by ChEMBL
Affinity DataEC50: 56nMAssay Description:Cell Handling: PathHunter NHR cell lines were expanded from freezer stocks according to standard procedures. Cells were seeded in a total volume of 2...More data for this Ligand-Target Pair
Affinity DataEC50: 5.06nMAssay Description:Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Mitobridge
Curated by ChEMBL
Mitobridge
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Transactivation of yeast GAL4 DNA binding domain-fused PPARgamma LBD (unknown origin) expressed in CV-1 cells after 24 hrs by luciferase reporter gen...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Temple University
Curated by ChEMBL
Temple University
Curated by ChEMBL
Affinity DataKd: 57nMAssay Description:Binding affinity to His-tagged PPARdelta (unknown origin) by SPR assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Temple University
Curated by ChEMBL
Temple University
Curated by ChEMBL
Affinity DataEC50: 5nMAssay Description:Activation of human PPARdelta LBD expressed in CHO-K1 cells by beta galactosidase enzyme fragment complement based fluorescence assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Mitobridge
Curated by ChEMBL
Mitobridge
Curated by ChEMBL
Affinity DataEC50: 6.10E+3nMAssay Description:Transactivation of yeast GAL4 DNA binding domain-fused PPARalpha LBD (unknown origin) expressed in CV-1 cells after 24 hrs by luciferase reporter gen...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Mitobridge
Curated by ChEMBL
Mitobridge
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of human PPARgamma LBD expressed in CHO-K1 cells by beta galactosidase enzyme fragment complement based fluorescence assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Temple University
Curated by ChEMBL
Temple University
Curated by ChEMBL
Affinity DataEC50: 37nMAssay Description:Transactivation of yeast GAL4 DNA binding domain-fused PPARdelta LBD (unknown origin) expressed in CV-1 cells after 24 hrs by luciferase reporter gen...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Mitobridge
Curated by ChEMBL
Mitobridge
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of human PPARalpha LBD expressed in CHO-K1 cells by beta galactosidase enzyme fragment complement based fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 270nMAssay Description:Transactivation of mouse PPARdelta by cell-based luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Temple University
Curated by ChEMBL
Temple University
Curated by ChEMBL
Affinity DataEC50: 37nMAssay Description:Transactivation of GAL4-fused human PPARdelta LBD expressed in African green monkey CV1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Mitobridge
Curated by ChEMBL
Mitobridge
Curated by ChEMBL
Affinity DataEC50: 6.10E+3nMAssay Description:Transactivation of GAL4-fused human PPARalpha LBD expressed in African green monkey CV1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Mitobridge
Curated by ChEMBL
Mitobridge
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Transactivation of GAL4-fused human PPARgamma LBD expressed in African green monkey CV1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Temple University
Curated by ChEMBL
Temple University
Curated by ChEMBL
Affinity DataEC50: 37nMAssay Description:Modulator activity at GAL4-fused human PPARdelta LBD (128 to residue at C-terminus) transfected in African green monkey CV1 cells assessed as recepto...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Mitobridge
Curated by ChEMBL
Mitobridge
Curated by ChEMBL
Affinity DataEC50: 6.10E+3nMAssay Description:Modulator activity at GAL4-fused human PPARalpha LBD (unknown origin) transfected in African green monkey CV1 cells assessed as receptor transactivat...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Temple University
Curated by ChEMBL
Temple University
Curated by ChEMBL
Affinity DataEC50: 5.10nMAssay Description:Transactivation of ProLink tagged human PPARdelta transfected in CHO-K1 cells assessed as interaction with EA labelled SRCP after 3 to 16 hrs by beta...More data for this Ligand-Target Pair