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BDBM50193035 CHEMBL3961335

SMILES: C=CCc1ccccc1NCC1=NCCN1

InChI Key: InChIKey=IYFFDNHPGFKOCO-UHFFFAOYSA-N

Data: 1 KI  2 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50193035   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Imidazoline I1


(RAT)
BDBM50193035
PNG
(CHEMBL3961335)
Show SMILES C=CCc1ccccc1NCC1=NCCN1
Show InChI InChI=1S/C13H17N3/c1-2-5-11-6-3-4-7-12(11)16-10-13-14-8-9-15-13/h2-4,6-7,16H,1,5,8-10H2,(H,14,15)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
4n/an/an/an/an/an/an/an/a



University of Camerino

Curated by ChEMBL


Assay Description
Displacement of [125I]-p-iodoclonidine from I1 receptor imidazoline binding site in Sprague-Dawley rat kidney cell membranes after 30 mins by liquid ...


ACS Med Chem Lett 7: 956-961 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00290
BindingDB Entry DOI: 10.7270/Q2086784
More data for this
Ligand-Target Pair
Alpha-2B adrenergic receptor


(Homo sapiens)
BDBM50193035
PNG
(CHEMBL3961335)
Show SMILES C=CCc1ccccc1NCC1=NCCN1
Show InChI InChI=1S/C13H17N3/c1-2-5-11-6-3-4-7-12(11)16-10-13-14-8-9-15-13/h2-4,6-7,16H,1,5,8-10H2,(H,14,15)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 2.51E+3n/an/an/an/a



University of Camerino

Curated by ChEMBL


Assay Description
Agonist activity at human alpha2b-AR expressed in CHO cells assessed as rate of acidification after 240 mins by cytosensor microphysiometric analysis


ACS Med Chem Lett 7: 956-961 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00290
BindingDB Entry DOI: 10.7270/Q2086784
More data for this
Ligand-Target Pair
Alpha-2C adrenergic receptor


(Homo sapiens (Human))
BDBM50193035
PNG
(CHEMBL3961335)
Show SMILES C=CCc1ccccc1NCC1=NCCN1
Show InChI InChI=1S/C13H17N3/c1-2-5-11-6-3-4-7-12(11)16-10-13-14-8-9-15-13/h2-4,6-7,16H,1,5,8-10H2,(H,14,15)
UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 158n/an/an/an/a



University of Camerino

Curated by ChEMBL


Assay Description
Agonist activity at human alpha2c-AR expressed in CHO cells assessed as rate of acidification after 240 mins by cytosensor microphysiometric analysis


ACS Med Chem Lett 7: 956-961 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00290
BindingDB Entry DOI: 10.7270/Q2086784
More data for this
Ligand-Target Pair