BDBM50194571 CHEMBL221444::N-phenyl-N'-{2-phenyl-3-[1-(tetrahydro-pyran-4-yl)-piperidin-4-ylmethyl]-quinoline-4-carbonyl}-hydrazinecarboxylic acid methyl ester

SMILES COC(=O)N(NC(=O)c1c(CC2CCN(CC2)C2CCOCC2)c(nc2ccccc12)-c1ccccc1)c1ccccc1

InChI Key InChIKey=XCHBXYOIQFUWBY-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50194571   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194571(CHEMBL221444 | N-phenyl-N'-{2-phenyl-3-[1-(tetrahy...)
Affinity DataKi:  8.00E+3nMAssay Description:Displacement of labeled MK499 from cloned hERG potassium channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194571(CHEMBL221444 | N-phenyl-N'-{2-phenyl-3-[1-(tetrahy...)
Affinity DataIC50:  5.70nMAssay Description:Displacement of [125I]neurokinin B from human cloned NK3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed