BDBM50194630 (R)-3-{4-[3-(4-chloro-2-phenoxy-phenoxy)-butoxy]-2-ethyl-phenyl}-propionic acid::CHEMBL215701

SMILES CCc1cc(OCC[C@@H](C)Oc2ccc(Cl)cc2Oc2ccccc2)ccc1CCC(O)=O

InChI Key InChIKey=CIPGEDLLCCHFDI-LJQANCHMSA-N

Data  6 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50194630   

TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50194630((R)-3-{4-[3-(4-chloro-2-phenoxy-phenoxy)-butoxy]-2...)
Affinity DataIC50:  4nMAssay Description:Displacement of [3H]2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from human PPARdelta by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50194630((R)-3-{4-[3-(4-chloro-2-phenoxy-phenoxy)-butoxy]-2...)
Affinity DataIC50:  19nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-[propyl-(5-pyridin-2-yl-thiophene-2-sulfonyl)-amino]-propyl}-phenoxy)-propionic acid from human PPARgamma by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50194630((R)-3-{4-[3-(4-chloro-2-phenoxy-phenoxy)-butoxy]-2...)
Affinity DataEC50:  2.80E+3nMAssay Description:Transactivation of human PPARalpha in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50194630((R)-3-{4-[3-(4-chloro-2-phenoxy-phenoxy)-butoxy]-2...)
Affinity DataEC50:  102nMAssay Description:Transactivation of human PPARgamma in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50194630((R)-3-{4-[3-(4-chloro-2-phenoxy-phenoxy)-butoxy]-2...)
Affinity DataIC50:  19.0nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50194630((R)-3-{4-[3-(4-chloro-2-phenoxy-phenoxy)-butoxy]-2...)
Affinity DataIC50:  6.93E+3nMAssay Description:Displacement of [3H]2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from human PPARalpha by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50194630((R)-3-{4-[3-(4-chloro-2-phenoxy-phenoxy)-butoxy]-2...)
Affinity DataIC50:  6.93E+3nMAssay Description:Agonist activity at PPARalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50194630((R)-3-{4-[3-(4-chloro-2-phenoxy-phenoxy)-butoxy]-2...)
Affinity DataIC50:  4nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50194630((R)-3-{4-[3-(4-chloro-2-phenoxy-phenoxy)-butoxy]-2...)
Affinity DataEC50:  6nMAssay Description:Transactivation of human PPARdelta in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed