BDBM50194695 4-methyl-N-(2-methyl-3-(trifluoromethyl)phenyl)-3-(2-(2-morpholinoethylamino)quinazolin-6-yl)benzamide::CHEMBL213290

SMILES Cc1ccc(cc1-c1ccc2nc(NCCN3CCOCC3)ncc2c1)C(=O)Nc1cccc(c1C)C(F)(F)F

InChI Key InChIKey=HQMQBWSLPHAVOU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50194695   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50194695(4-methyl-N-(2-methyl-3-(trifluoromethyl)phenyl)-3-...)
Affinity DataIC50:  40nMAssay Description:Inhibition of p38-alpha by HTRF kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50194695(4-methyl-N-(2-methyl-3-(trifluoromethyl)phenyl)-3-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of KDR by HTRF kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50194695(4-methyl-N-(2-methyl-3-(trifluoromethyl)phenyl)-3-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Lck by HTRF kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50194695(4-methyl-N-(2-methyl-3-(trifluoromethyl)phenyl)-3-...)
Affinity DataIC50:  626nMAssay Description:Inhibition of Jak3 by HTRF kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed