BDBM50194747 ((R)-4-bromo-3,6-dimethoxybenzocyclobuten-1-yl)methylamine::CHEMBL379637

SMILES COc1cc(Br)c(OC)c2C[C@@H](CN)c12

InChI Key InChIKey=MPBCKKVERDTCEL-LURJTMIESA-N

Data  2 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50194747   

Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50194747(((R)-4-bromo-3,6-dimethoxybenzocyclobuten-1-yl)met...)
Affinity DataKi:  0.260nMAssay Description:Displacement of (+/-)-[125I]DOI from rat cloned 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50194747(((R)-4-bromo-3,6-dimethoxybenzocyclobuten-1-yl)met...)
Affinity DataKi:  0.350nMAssay Description:Displacement of (+/-)-[125I]DOI from human cloned 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50194747(((R)-4-bromo-3,6-dimethoxybenzocyclobuten-1-yl)met...)
Affinity DataEC50:  1.12E+3nMAssay Description:Activity at rat 5HT2A receptor expressed in NIH3T3 cells assessed as stimulation of 2-arachidonylglycerol productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50194747(((R)-4-bromo-3,6-dimethoxybenzocyclobuten-1-yl)met...)
Affinity DataEC50:  1.18E+3nMAssay Description:Activity at rat 5HT2A receptor expressed in NIH3T3 cells assessed as stimulation of arachidonic acid releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50194747(((R)-4-bromo-3,6-dimethoxybenzocyclobuten-1-yl)met...)
Affinity DataEC50:  18nMAssay Description:Activity at rat 5HT2A receptor expressed in NIH3T3 cells assessed as stimulation of phospholipase C-mediated IP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed