BDBM50194900 CHEMBL218657::N-(4-(methylsulfonyl)benzyl)-4-amino-5-cyano-6-(prop-1-enyl)picolinamide

SMILES C\C=C/c1nc(cc(N)c1C#N)C(=O)NCc1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=MXRSDWOBSNRDKJ-ARJAWSKDSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50194900   

TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50194900(CHEMBL218657 | N-(4-(methylsulfonyl)benzyl)-4-amin...)
Affinity DataIC50:  150nMAssay Description:Inhibition of JNK1 by ATF2 phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50194900(CHEMBL218657 | N-(4-(methylsulfonyl)benzyl)-4-amin...)
Affinity DataIC50:  150nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50194900(CHEMBL218657 | N-(4-(methylsulfonyl)benzyl)-4-amin...)
Affinity DataIC50:  260nMAssay Description:Inhibition of JNK2 by ATF2 phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed