BDBM50195246 CHEMBL3980602::US10287258, Example 16::US10669245, Example 16::US11117874, Example 16::US11655221, Example 16
SMILES CCn1c2cc(ccc2oc1=O)-c1ccc(C[C@H](NC(=O)[C@@H]2CNCCCO2)C#N)cc1
InChI Key InChIKey=HZZYFVOLMKQYKP-UGKGYDQZSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50195246
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant DPP1 using Gly-Arg-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorometric assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of DPP1 in human U937 cells using Gly-Phe-AFC as substrate preincubated for 60 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 5.75nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 5.75nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 5.75nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 5.75nMAssay Description:Examples 1-35: The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 5.75nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair