BDBM50195495 3-((2R,6R)-1-(4-amino-3,5-dichlorobenzoyl)-2,6-dimethylpiperidin-4-yl)benzo[d]oxazol-2(3H)-one::CHEMBL435136

SMILES C[C@@H]1CC(C[C@@H](C)N1C(=O)c1cc(Cl)c(N)c(Cl)c1)n1c2ccccc2oc1=O

InChI Key InChIKey=QZRRAORQYWPWHA-VXGBXAGGSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50195495   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195495(3-((2R,6R)-1-(4-amino-3,5-dichlorobenzoyl)-2,6-dim...)
Affinity DataKi:  12nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195495(3-((2R,6R)-1-(4-amino-3,5-dichlorobenzoyl)-2,6-dim...)
Affinity DataKi:  160nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195495(3-((2R,6R)-1-(4-amino-3,5-dichlorobenzoyl)-2,6-dim...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human 11beta-HSD2 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195495(3-((2R,6R)-1-(4-amino-3,5-dichlorobenzoyl)-2,6-dim...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195495(3-((2R,6R)-1-(4-amino-3,5-dichlorobenzoyl)-2,6-dim...)
Affinity DataIC50:  72nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells by fluorescence polarization immuno-assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed