BDBM50195783 CHEMBL3907708

SMILES COC(=O)[C@H]1CNC[C@H](C1)N(CC(C)C)C(=O)c1cnc(nc1NCc1ccco1)C(C)(C)C

InChI Key InChIKey=XWKPQIHEQDPCKK-MSOLQXFVSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50195783   

TargetRenin(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50195783(CHEMBL3907708)
Affinity DataIC50:  0.0390nMAssay Description:Inhibition of recombinant human preprorenin expressed in human 293F cells using angiotensinogen as substrate preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50195783(CHEMBL3907708)
Affinity DataIC50:  0.350nMAssay Description:Inhibition of renin in human plasma by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50195783(CHEMBL3907708)
Affinity DataIC50:  0.0390nMAssay Description:Inhibition of recombinant human preprorenin expressed in human 293F cells using angiotensinogen as substrate preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50195783(CHEMBL3907708)
Affinity DataIC50:  0.350nMAssay Description:Inhibition of renin in human plasma by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed