BDBM50196032 (N-[(2-tert-butylbenzenesulfonyl)phenyl]-2,3,4-trihydroxy-5-(2-isopropylbenzyl)benzamide::CHEMBL217354::N-[(2-tert-butyl-benzenesulfonyl)-phenyl]-2,3,4-trihydroxy-5-(2-isopropyl-benzyl)-benzamide::TW-37
SMILES CC(C)c1ccccc1Cc1cc(C(=O)Nc2ccc(cc2)S(=O)(=O)c2ccccc2C(C)(C)C)c(O)c(O)c1O
InChI Key InChIKey=PQAPVTKIEGUPRN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50196032
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Xihua University
Curated by ChEMBL
Xihua University
Curated by ChEMBL
Affinity DataKi: 260nMAssay Description:Inhibition of FAM-Bid BH3 peptide binding to recombinant human MCL1 by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Xihua University
Curated by ChEMBL
Xihua University
Curated by ChEMBL
Affinity DataKi: 260nMAssay Description:Displacement of FAM-Bid from human Mcl1 by FP assayMore data for this Ligand-Target Pair
Affinity DataKi: 290nMAssay Description:Inhibition of FAM-Bid BH3 peptide binding to recombinant human BCL2 by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 290nMAssay Description:Displacement of FAM-Bid from human Bcl2 by FP assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.11E+3nMAssay Description:Displacement of FAM-Bid peptide from human recombinant Bcl-xL by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.11E+3nMAssay Description:Inhibition of FAM-Bid BH3 peptide binding to recombinant human BCL-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.11E+3nMAssay Description:Displacement of FAM-Bak from human Bcl-xL by FP assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Xihua University
Curated by ChEMBL
Xihua University
Curated by ChEMBL
Affinity DataKd: 4.63E+3nMAssay Description:Binding affinity to human N-terminal His-tagged SIRT5 (34 to 302 residues) expressed in Escherichia coli at 600 uM by isothermal titration calorimetr...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Xihua University
Curated by ChEMBL
Xihua University
Curated by ChEMBL
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of human N-terminal His-tagged SIRT5 (34 to 302 residues) expressed in Escherichia coli using Ac-His-Phe-Ser-Lys(Su)-AMC as substrate prei...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Xihua University
Curated by ChEMBL
Xihua University
Curated by ChEMBL
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of human N-terminal His-tagged SIRT5 (34 to 302 residues) expressed in Escherichia coli using Ac-Leu-Gly-Ser-Lys(Su)-AMC as substrate prei...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Xihua University
Curated by ChEMBL
Xihua University
Curated by ChEMBL
Affinity DataIC50: 2.19E+4nMAssay Description:Inhibition of human N-terminal His-tagged SIRT5 (34 to 302 residues) expressed in Escherichia coli using Ac-Tyr-Lys-Leu-Lys(Ac)-AMC as substrate prei...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of growth of human PC3 cell overexpressing Bcl2More data for this Ligand-Target Pair
Affinity DataIC50: 6.58E+3nMAssay Description:Displacement of FAM-Bak from human Bcl-xL by FP assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Xihua University
Curated by ChEMBL
Xihua University
Curated by ChEMBL
Affinity DataIC50: 1.03E+3nMAssay Description:Displacement of FAM-Bid from human Mcl1 by FP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Binding affinity to human Bcl2 by ELISAMore data for this Ligand-Target Pair