BDBM50196036 CHEMBL217223::N-(benzenesulfonyl-phenyl)-2,3,4-trihydroxy-5-benzyl-benzamide

SMILES Oc1c(O)c(Cc2ccccc2)cc(C(=O)Nc2ccc(cc2)S(=O)(=O)c2ccccc2)c1O

InChI Key InChIKey=CGSIJNKVBVZVLU-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50196036   

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50196036(CHEMBL217223 | N-(benzenesulfonyl-phenyl)-2,3,4-tr...)
Affinity DataKi:  930nMAssay Description:Displacement of FAM-Bid from human Bcl2 by FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50196036(CHEMBL217223 | N-(benzenesulfonyl-phenyl)-2,3,4-tr...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of growth of human PC3 cell overexpressing Bcl2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50196036(CHEMBL217223 | N-(benzenesulfonyl-phenyl)-2,3,4-tr...)
Affinity DataIC50:  1.60E+3nMAssay Description:Binding affinity to human Bcl2 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed