BDBM50197123 CHEMBL214768::N-(1-(3-fluoro-4-methoxybenzyl)piperidin-4-yl)-7-fluoro-4-oxo-4H-chromene-2-carboxamide::N-[1-[(3-fluoro-4-methoxybenzyl)methyl]piperidin-4-yl]-7-fluoro-4-oxo-4H-chromene-2-carboxamide
SMILES COc1ccc(CN2CCC(CC2)NC(=O)c2cc(=O)c3ccc(F)cc3o2)cc1F
InChI Key InChIKey=NKKHUNXEXXFYQF-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50197123
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 168nMAssay Description:Antagonist activity at MCHr1 assessed as inhibition of MCH-mediated calcium ion release in intact IMR32 cells by FLIPR assayMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Displacement of [125I]MCH from MCHr1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Displacement of [125I]MCH from MCHR1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 168nMAssay Description:Antagonist activity at MCHR1 assessed as inhibition of MCH-mediated calcium release in IMR32 cellsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 8.30E+3nMAssay Description:Displacement of [3H]dofetilide from hERG expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 8.5nMAssay Description:Displacement of [3H]dofetilide from hERGMore data for this Ligand-Target Pair