BDBM50197885 CHEMBL3940890

SMILES Cc1n[nH]c(C)c1CCCOc1cc(ccc1F)C(O)=O

InChI Key InChIKey=WBFUHHBPNXWNCC-UHFFFAOYSA-N

Data  2 IC50  5 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50197885   

TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50197885(CHEMBL3940890)
Affinity DataKd:  4.80nMAssay Description:Binding affinity to human plasma wild type TTR assessed as dissociation constants for second binding site of TTR by isothermal titration calorimetric...More data for this Ligand-Target Pair
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50197885(CHEMBL3940890)
Affinity DataKd:  314nMAssay Description:Binding affinity to human plasma wild type TTR assessed as dissociation constants for first binding site of TTR by isothermal titration calorimetric ...More data for this Ligand-Target Pair
TargetAlbumin(Homo sapiens (Human))
University Of The Pacific

Curated by ChEMBL
LigandPNGBDBM50197885(CHEMBL3940890)
Affinity DataKd:  8.00E+3nMAssay Description:Binding affinity to human serum albumin by ITC methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50197885(CHEMBL3940890)
Affinity DataKd:  7.30nMAssay Description:Binding affinity to human TTR incubated for 20 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50197885(CHEMBL3940890)
Affinity DataIC50:  160nMAssay Description:Binding affinity to human plasma TTR tetramer assessed as displacement of diclofenac-coupled FITC by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetRetinol-binding protein 4(Homo sapiens (Human))
Albany College Of Pharmacy And Health Sciences

Curated by ChEMBL
LigandPNGBDBM50197885(CHEMBL3940890)
Affinity DataIC50: >3.00E+4nMAssay Description:Displacement of [3H]-all trans retinol from human urine biotinylated RBP4 incubated for 16 hrs measured by Scintillation Proximity AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50197885(CHEMBL3940890)
Affinity DataKd:  4.80nMAssay Description:Binding affinity to transthyretin (unknown origin) by ITC methodMore data for this Ligand-Target Pair