BDBM50198573 (S)-1-(6-((diethylamino)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)-4-(4-fluorophenethyl)piperazin-2-one::(S)-4-(4-fluorophenethyl)-1-(6-((diethylamino)-methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)piperazin-2-one::CHEMBL214629

SMILES CCN(CC)Cc1ccc2C[C@H](CCc2c1)N1CCN(CCc2ccc(F)cc2)CC1=O

InChI Key InChIKey=XWZAXTGZXFCRFU-SANMLTNESA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50198573   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198573((S)-1-(6-((diethylamino)methyl)-1,2,3,4-tetrahydro...)
Affinity DataKi:  3nMAssay Description:Binding affinity at MCHR1 by flash plate radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198573((S)-1-(6-((diethylamino)methyl)-1,2,3,4-tetrahydro...)
Affinity DataKi:  15nMAssay Description:Inhibition of binding to MCH-R1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198573((S)-1-(6-((diethylamino)methyl)-1,2,3,4-tetrahydro...)
Affinity DataIC50:  10nMAssay Description:Inhibition of MCHR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198573((S)-1-(6-((diethylamino)methyl)-1,2,3,4-tetrahydro...)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of binding to hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50198573((S)-1-(6-((diethylamino)methyl)-1,2,3,4-tetrahydro...)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed