BDBM50199034 5-[(5R,9S)-9-(4-cyano-phenyl)-3-(3,5-dichloro-phenyl)-1-methyl-2,4-dioxo-1,3,7-triaza-spiro[4.4]non-7-ylmethyl]-thiophene-3-carboxylic acid::CHEMBL424898
SMILES CN1C(=O)N(C(=O)[C@@]11CN(Cc2cc(cs2)C(O)=O)C[C@@H]1c1ccc(cc1)C#N)c1cc(Cl)cc(Cl)c1
InChI Key InChIKey=NXNKJLOEGWSJGI-GJZUVCINSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50199034
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Cerep
Curated by ChEMBL
Cerep
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of LFA1-mediated adhesion of T cell to HUVECMore data for this Ligand-Target Pair