BDBM50199261 6-(4-chlorophenyl)-3-(2-{[(3R)-3-hydroxypyrrolidin-1-yl]-methyl}-1-benzothien-5-yl)thieno[3,2-d]pyrimidin-4(3H)-one::CHEMBL262945

SMILES O[C@@H]1CCN(Cc2cc3cc(ccc3s2)-n2cnc3cc(sc3c2=O)-c2ccc(Cl)cc2)C1

InChI Key InChIKey=ZDFHQJRHOKOKEF-LJQANCHMSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50199261   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50199261(6-(4-chlorophenyl)-3-(2-{[(3R)-3-hydroxypyrrolidin...)
Affinity DataIC50:  2.5nMAssay Description:Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed