BDBM50199303 8-(4-hydroxybicyclo[2.2.2]octan-1-yl)-1,3-dipropyl-1H-purine-2,6(3H,7H)-dione::CHEMBL218458

SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C12CCC(O)(CC1)CC2

InChI Key InChIKey=JMEHHVKPUQMNOZ-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50199303   

TargetAdenosine receptor A1(Rattus norvegicus (rat))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50199303(8-(4-hydroxybicyclo[2.2.2]octan-1-yl)-1,3-dipropyl...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50199303(8-(4-hydroxybicyclo[2.2.2]octan-1-yl)-1,3-dipropyl...)
Affinity DataKi:  2nMAssay Description:Displacement of [125I]ABA from human adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50199303(8-(4-hydroxybicyclo[2.2.2]octan-1-yl)-1,3-dipropyl...)
Affinity DataKi:  430nMAssay Description:Displacement of [125I]3-(4-aminobenzyl)-8-phenyloxyacetate-1-propyl-xanthine from human adenosine A2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50199303(8-(4-hydroxybicyclo[2.2.2]octan-1-yl)-1,3-dipropyl...)
Affinity DataKi:  550nMAssay Description:Displacement of [125I]ZM241385 from human adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50199303(8-(4-hydroxybicyclo[2.2.2]octan-1-yl)-1,3-dipropyl...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [125I]ABA from human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed