BDBM50199493 1-(N-((1r,4r)-4-tert-butylcyclohexyl)-2-(4-(trifluoromethoxy)phenyl)acetamido)-N-(2H-tetrazol-5-yl)-2,3-dihydro-1H-indene-5-carboxamide::CHEMBL232242

SMILES CC(C)(C)[C@H]1CC[C@@H](CC1)N(C1CCc2cc(ccc12)C(=O)Nc1nnn[nH]1)C(=O)Cc1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=SQCUILFEAKKVAC-RFJGZHNSSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50199493   

TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199493(1-(N-((1r,4r)-4-tert-butylcyclohexyl)-2-(4-(triflu...)
Affinity DataIC50:  67nMAssay Description:Antagonist activity at human glucagon receptor transfected in CHO cells assessed as inhibition of glucagon-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastric inhibitory polypeptide receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199493(1-(N-((1r,4r)-4-tert-butylcyclohexyl)-2-(4-(triflu...)
Affinity DataIC50:  118nMAssay Description:Antagonist activity at human GIP receptor transfected in CHO cells assessed as inhibition of glucagon-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199493(1-(N-((1r,4r)-4-tert-butylcyclohexyl)-2-(4-(triflu...)
Affinity DataIC50:  4.80nMAssay Description:Displacement of [125]glucagon from human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed