BDBM50199493 1-(N-((1r,4r)-4-tert-butylcyclohexyl)-2-(4-(trifluoromethoxy)phenyl)acetamido)-N-(2H-tetrazol-5-yl)-2,3-dihydro-1H-indene-5-carboxamide::CHEMBL232242
SMILES CC(C)(C)[C@H]1CC[C@@H](CC1)N(C1CCc2cc(ccc12)C(=O)Nc1nnn[nH]1)C(=O)Cc1ccc(OC(F)(F)F)cc1
InChI Key InChIKey=SQCUILFEAKKVAC-RFJGZHNSSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50199493
Affinity DataIC50: 67nMAssay Description:Antagonist activity at human glucagon receptor transfected in CHO cells assessed as inhibition of glucagon-induced cAMP accumulationMore data for this Ligand-Target Pair
TargetGastric inhibitory polypeptide receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 118nMAssay Description:Antagonist activity at human GIP receptor transfected in CHO cells assessed as inhibition of glucagon-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Displacement of [125]glucagon from human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair