BDBM50199496 3-(1-(1-((1r,4r)-4-tert-butylcyclohexyl)-3-(3,5-dichlorophenyl)ureido)-2,3-dihydro-1H-indene-5-carboxamido)propanoic acid::CHEMBL430163

SMILES CC(C)(C)[C@H]1CC[C@@H](CC1)N(C1CCc2cc(ccc12)C(=O)NCCC(O)=O)C(=O)Nc1cc(Cl)cc(Cl)c1

InChI Key InChIKey=GZGAUBCVTUVGJU-SUMMSQPPSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50199496   

TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199496(3-(1-(1-((1r,4r)-4-tert-butylcyclohexyl)-3-(3,5-di...)
Affinity DataIC50:  10nMAssay Description:Displacement of [125]glucagon from human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199496(3-(1-(1-((1r,4r)-4-tert-butylcyclohexyl)-3-(3,5-di...)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at human glucagon receptor transfected in CHO cells assessed as inhibition of glucagon-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastric inhibitory polypeptide receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199496(3-(1-(1-((1r,4r)-4-tert-butylcyclohexyl)-3-(3,5-di...)
Affinity DataIC50:  1.28E+3nMAssay Description:Antagonist activity at human GIP receptor transfected in CHO cells assessed as inhibition of glucagon-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed