BDBM50200249 2-(4-bromo-2-(isoxazole-5-carbonyl)phenoxy)acetic acid::CHEMBL386370

SMILES OC(=O)COc1ccc(Br)cc1C(=O)c1ccno1

InChI Key InChIKey=ITWPZOSVLCTNIX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50200249   

TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200249(2-(4-bromo-2-(isoxazole-5-carbonyl)phenoxy)acetic ...)
Affinity DataIC50:  2.65E+3nMAssay Description:Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50200249(2-(4-bromo-2-(isoxazole-5-carbonyl)phenoxy)acetic ...)
Affinity DataIC50:  391nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed