BDBM50200376 CHEMBL3896323

SMILES CC(=O)N1CCc2c(C1)c(Nc1ccc(cc1)-c1cnn(C)c1)nn2[C@@H]1CCOC1

InChI Key InChIKey=ZNIQPKLUCOYTFF-LJQANCHMSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50200376   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50200376(CHEMBL3896323)
Affinity DataIC50:  8.50E+3nMAssay Description:Displacement of biotinylated ligand from recombinant His-tagged BRD4 bromodomain-1 (unknown origin) measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein/Histone acetyltransferase p300(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50200376(CHEMBL3896323)
Affinity DataIC50:  20nMAssay Description:Displacement of biotinylated ligand from recombinant His-tagged CBP/EP300 (unknown origin) measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein/Histone acetyltransferase p300(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50200376(CHEMBL3896323)
Affinity DataIC50:  730nMAssay Description:Inhibition of Halo-tagged histone H3.3 binding to CBP/EP300 (unknown origin) expressed in HEK293 cells measured after overnight incubation by lucifer...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed