BDBM50200396 (R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-4-methylpent-3-enyl 3-methylbutanoate::CHEMBL395857

SMILES [#6]-[#6](-[#6])-[#6]-[#6](=O)-[#8]-[#6](=[#6]\[#6]=[#6](\[#6])-[#6])-c1cc(-[#8])c2c(-[#8])ccc(-[#8])c2c1-[#8]

InChI Key InChIKey=RCLASMSCTFWRIF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50200396   

TargetSterol O-acyltransferase 1(Homo sapiens (Human))
National Research Laboratory Of Lipid Metabolism And Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50200396((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  1.38E+4nMAssay Description:Inhibition of human ACAT1 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
National Research Laboratory Of Lipid Metabolism And Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50200396((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human ACAT1 expressed in AC29 cells by cell-based fluorescent assay systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 2(Homo sapiens (Human))
National Research Laboratory Of Lipid Metabolism And Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50200396((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  800nMAssay Description:Inhibition of human ACAT2 expressed in AC29 cells by cell-based fluorescent assay systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 2(Homo sapiens (Human))
National Research Laboratory Of Lipid Metabolism And Atherosclerosis

Curated by ChEMBL
LigandPNGBDBM50200396((R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50:  2.51E+4nMAssay Description:Inhibition of human ACAT2 expressed in Hi5 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed