BDBM50200425 CHEMBL3934488

SMILES CCCNC(=O)c1cccc(Nc2nn(CC3CC3)c3CCN(Cc23)C(C)=O)c1

InChI Key InChIKey=ZDLOIRATYRBXGM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50200425   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50200425(CHEMBL3934488)
Affinity DataIC50:  5.80E+3nMAssay Description:Displacement of biotinylated ligand from recombinant His-tagged BRD4 bromodomain-1 (unknown origin) measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein/Histone acetyltransferase p300(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50200425(CHEMBL3934488)
Affinity DataIC50:  30nMAssay Description:Displacement of biotinylated ligand from recombinant His-tagged CBP/EP300 (unknown origin) measured after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein/Histone acetyltransferase p300(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50200425(CHEMBL3934488)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of Halo-tagged histone H3.3 binding to CBP/EP300 (unknown origin) expressed in HEK293 cells measured after overnight incubation by lucifer...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed