BDBM50200788 2-(4-chlorophenoxy)-N-(4-methyl-2-(pyrrolidin-1-yl)quinazolin-6-yl)acetamide::ADS-103253::CHEMBL216228

SMILES Cc1nc(nc2ccc(NC(=O)COc3ccc(Cl)cc3)cc12)N1CCCC1

InChI Key InChIKey=MXDQNCXNQJMIEH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50200788   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200788(2-(4-chlorophenoxy)-N-(4-methyl-2-(pyrrolidin-1-yl...)
Affinity DataIC50:  58nMAssay Description:Inhibition of MCH-mediated calcium influx into MCH-R1 expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200788(2-(4-chlorophenoxy)-N-(4-methyl-2-(pyrrolidin-1-yl...)
Affinity DataIC50:  250nMAssay Description:Displacement of 125I-[Phe13,Tyr19]-MCH from MCH-R1 expressing cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200788(2-(4-chlorophenoxy)-N-(4-methyl-2-(pyrrolidin-1-yl...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of 5HT2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200788(2-(4-chlorophenoxy)-N-(4-methyl-2-(pyrrolidin-1-yl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of D2(L)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200788(2-(4-chlorophenoxy)-N-(4-methyl-2-(pyrrolidin-1-yl...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of hERG in patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed