BDBM50201363 1-methyl-4-(pyridin-4-ylmethylamino)-N-(4-(trifluoromethoxy)phenyl)-1H-pyrazole-5-carboxamide::CHEMBL401040

SMILES Cn1ncc(NCc2ccncc2)c1C(=O)Nc1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=MCIJHEGABQVOTC-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50201363   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201363(1-methyl-4-(pyridin-4-ylmethylamino)-N-(4-(trifluo...)
Affinity DataKi:  0.170nMAssay Description:Inhibition of VEGFR2 by [32P]ATP-competitive radioassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201363(1-methyl-4-(pyridin-4-ylmethylamino)-N-(4-(trifluo...)
Affinity DataIC50:  64nMAssay Description:Inhibition of VEGFR2 by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201363(1-methyl-4-(pyridin-4-ylmethylamino)-N-(4-(trifluo...)
Affinity DataIC50:  730nMAssay Description:Inhibition of VEGFR1 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201363(1-methyl-4-(pyridin-4-ylmethylamino)-N-(4-(trifluo...)
Affinity DataIC50:  1.87E+3nMAssay Description:Inhibition of VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed