BDBM50202379 (RR/SS)-2-[1-(4-methoxyphenyl)-3-methylbutyl]piperidine::(RS/SR)-2-[1-(4-methoxyphenyl)-3-methylbutyl]piperidine::CHEMBL218894

SMILES COc1ccc(cc1)C(CC(C)C)C1CCCCN1

InChI Key InChIKey=HWQHDSKQNMHWMT-UHFFFAOYSA-N

Data  6 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50202379   

TargetSodium-dependent dopamine transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202379((RR/SS)-2-[1-(4-methoxyphenyl)-3-methylbutyl]piper...)
Affinity DataKi:  52nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202379((RR/SS)-2-[1-(4-methoxyphenyl)-3-methylbutyl]piper...)
Affinity DataKi:  52nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202379((RR/SS)-2-[1-(4-methoxyphenyl)-3-methylbutyl]piper...)
Affinity DataKi:  2.80E+3nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202379((RR/SS)-2-[1-(4-methoxyphenyl)-3-methylbutyl]piper...)
Affinity DataKi:  2.80E+3nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202379((RR/SS)-2-[1-(4-methoxyphenyl)-3-methylbutyl]piper...)
Affinity DataKi:  3.10E+3nMAssay Description:Displacement of [125I]RTI-55 from human NET expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202379((RR/SS)-2-[1-(4-methoxyphenyl)-3-methylbutyl]piper...)
Affinity DataKi:  3.10E+3nMAssay Description:Displacement of [125I]RTI-55 from human NET expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202379((RR/SS)-2-[1-(4-methoxyphenyl)-3-methylbutyl]piper...)
Affinity DataIC50:  410nMAssay Description:Inhibition of [3H]NE uptake into human NET expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202379((RR/SS)-2-[1-(4-methoxyphenyl)-3-methylbutyl]piper...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of [3H]5-HT uptake into human SERT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202379((RR/SS)-2-[1-(4-methoxyphenyl)-3-methylbutyl]piper...)
Affinity DataIC50:  25nMAssay Description:Inhibition of [3H]DA uptake at human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202379((RR/SS)-2-[1-(4-methoxyphenyl)-3-methylbutyl]piper...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of [3H]5-HT uptake into human SERT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202379((RR/SS)-2-[1-(4-methoxyphenyl)-3-methylbutyl]piper...)
Affinity DataIC50:  25nMAssay Description:Inhibition of [3H]DA uptake at human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202379((RR/SS)-2-[1-(4-methoxyphenyl)-3-methylbutyl]piper...)
Affinity DataIC50:  410nMAssay Description:Inhibition of [3H]NE uptake into human NET expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed