BDBM50203229 CHEMBL3980903
SMILES Cn1cc(-c2c(N)nc(N)nc2C2CC2)c2ccccc12
InChI Key InChIKey=YXHFJTDWWPFAGS-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50203229
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Turing Pharmaceuticals
Curated by ChEMBL
Turing Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 460nMAssay Description:Inhibition of Toxoplasma gondii TS-DHFR expressed in Escherichia coli BL21 preincubated for 15 mins followed by addition of DHF as substrate and NADP...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of recombinant human DHFR expressed in Escherichia coli preincubated for 15 mins followed by addition of DHF as substrate and NADPH measur...More data for this Ligand-Target Pair