BDBM50203275 CHEMBL3971417

SMILES Cc1n[nH]c2Oc3[nH]c(=O)[nH]c(=O)c3C(c12)c1ccc(F)c(F)c1

InChI Key InChIKey=QIMOSJIYZCZLKA-UHFFFAOYSA-N

Data  1 KI  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50203275   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50203275(CHEMBL3971417)
Affinity DataKi:  297nMAssay Description:Inhibition of N-terminus 6xHis-tagged human IDO1 expressed in Escherichia coli M15 using L-tryptophan as substrate preincubated for 1 hr measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50203275(CHEMBL3971417)
Affinity DataEC50:  76nMAssay Description:Inhibition of IDO1 in IFNgamma-induced human MDA-MB-231 cells using tryptophan as substrate preincubated for 4 hrs followed by substrate addition for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50203275(CHEMBL3971417)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of N-terminal 6xHis-tagged human TDO expressed in Escherichia cli Rosetta (DE3) pLysS using L-tryptophan as substrate preincubated for 1 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50203275(CHEMBL3971417)
Affinity DataIC50:  410nMAssay Description:Inhibition of N-terminus 6xHis-tagged human IDO1 expressed in Escherichia coli M15 using L-tryptophan as substrate preincubated for 1 hr measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Indian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50203275(CHEMBL3971417)
Affinity DataIC50:  78nMAssay Description:Inhibition of N-terminus 6xHis-tagged human IDO1 expressed in Escherichia coli M15 using L-tryptophan as substrate preincubated for 1 hr measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed