BDBM50203457 CHEMBL3985315

SMILES CN1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(c3)-c3nc(no3)-c3cccnc3)cc2C(F)(F)F)CC1

InChI Key InChIKey=QRHAJZCTCMFVCG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50203457   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50203457(CHEMBL3985315)
Affinity DataIC50:  12nMAssay Description:Inhibition of RET (unknown origin) using poly[Glu:Tyr] (4:1) as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed