BDBM50204882 CHEMBL375615::[4-(4-chloro-phenoxy)-piperidin-1-yl]-(6-hydroxy-1H-benzimidazol-2-yl)-methanone
SMILES Oc1cc2nc([nH]c2cc1O)C(=O)N1CCC(CC1)Oc1ccc(Cl)cc1
InChI Key InChIKey=GCTZJYDGWSFXMI-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50204882
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Gedeon Richter
Curated by ChEMBL
Gedeon Richter
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at NR2B NMDA receptor in Wistar rat neocortical cells assessed as inhibition of NMDA-evoked elevation of intracellular calcium co...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Gedeon Richter
Curated by ChEMBL
Gedeon Richter
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Displacement of [3H]Ro 25,6981 from NR2B NMDA receptor in rat forebrainMore data for this Ligand-Target Pair