BDBM50205632 CHEMBL3901570
SMILES CC(C)N1CC(C)c2c1cc(cc2C(=O)NCc1c(C)cc(C)[nH]c1=O)-c1ccc(nc1)N1CCNCC1
InChI Key InChIKey=FEZWVJGCJOKBGK-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50205632
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of human wild type EZH2 using histone H3 as substrate after 1 hr in presence of 3H-SAM by filter paper detection analysisMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH1(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 1.87E+3nMAssay Description:Inhibition of human EZH1 complex using histone H3 as substrate after 1 hr in presence of 3H-SAM by filter paper detection analysisMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of human wild type EZH2 using histone H3 as substrate after 1 hr in presence of 3H-SAM by filter paper detection analysisMore data for this Ligand-Target Pair