BDBM50205632 CHEMBL3901570

SMILES CC(C)N1CC(C)c2c1cc(cc2C(=O)NCc1c(C)cc(C)[nH]c1=O)-c1ccc(nc1)N1CCNCC1

InChI Key InChIKey=FEZWVJGCJOKBGK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50205632   

TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50205632(CHEMBL3901570)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of human wild type EZH2 using histone H3 as substrate after 1 hr in presence of 3H-SAM by filter paper detection analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EZH1(Homo sapiens (Human))
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50205632(CHEMBL3901570)
Affinity DataIC50:  1.87E+3nMAssay Description:Inhibition of human EZH1 complex using histone H3 as substrate after 1 hr in presence of 3H-SAM by filter paper detection analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50205632(CHEMBL3901570)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of human wild type EZH2 using histone H3 as substrate after 1 hr in presence of 3H-SAM by filter paper detection analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed