BDBM50206073 CHEMBL233652::N-[2-(2-pyridin-2-yl-ethylamino)-benzothiazol-6-yl]-thiophene-2-carboxamidine

SMILES NC(=Nc1ccc2nc(NCCc3ccccn3)sc2c1)c1cccs1

InChI Key InChIKey=DRFCDCAVGGNYKO-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50206073   

TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50206073(CHEMBL233652 | N-[2-(2-pyridin-2-yl-ethylamino)-be...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human inducible NOS activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Rattus norvegicus)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50206073(CHEMBL233652 | N-[2-(2-pyridin-2-yl-ethylamino)-be...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of rat inducible NOS activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Rattus norvegicus)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50206073(CHEMBL233652 | N-[2-(2-pyridin-2-yl-ethylamino)-be...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of rat endothelial NOS activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50206073(CHEMBL233652 | N-[2-(2-pyridin-2-yl-ethylamino)-be...)
Affinity DataIC50:  900nMAssay Description:Inhibition of human endothelial NOS activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50206073(CHEMBL233652 | N-[2-(2-pyridin-2-yl-ethylamino)-be...)
Affinity DataIC50:  50nMAssay Description:Inhibition of rat neuronal NOS activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50206073(CHEMBL233652 | N-[2-(2-pyridin-2-yl-ethylamino)-be...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human neuronal NOS activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed