BDBM50206286 5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(2,4-dimethylthiazol-5-yl)pyrimidin-2-amine::CHEMBL234451

SMILES CN(C)CCc1ccc(Nc2ncc(Cl)c(n2)-c2sc(C)nc2C)cc1

InChI Key InChIKey=QQQCVHLZASHOEP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50206286   

TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206286(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(2...)
Affinity DataIC50:  439nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206286(5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(2...)
Affinity DataIC50:  797nMAssay Description:Inhibiton of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed