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BDBM50206336 CHEMBL242961::N,N-dimethyl-1-[3-(4-octylphenoxy)-2-oxopropyl]indole-5-carboxamide

SMILES: CCCCCCCCc1ccc(OCC(=O)Cn2ccc3cc(ccc23)C(=O)N(C)C)cc1

InChI Key: InChIKey=VSHHPJNIKLWJMV-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50206336   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cPLA2 C2


(Homo sapiens (Human))
BDBM50206336
PNG
(CHEMBL242961 | N,N-dimethyl-1-[3-(4-octylphenoxy)-...)
Show SMILES CCCCCCCCc1ccc(OCC(=O)Cn2ccc3cc(ccc23)C(=O)N(C)C)cc1
Show InChI InChI=1S/C28H36N2O3/c1-4-5-6-7-8-9-10-22-11-14-26(15-12-22)33-21-25(31)20-30-18-17-23-19-24(13-16-27(23)30)28(32)29(2)3/h11-19H,4-10,20-21H2,1-3H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 840n/an/an/an/an/an/a



University of Münster

Curated by ChEMBL


Assay Description
Inhibition of human platelet cPLA2-alpha assessed as arachidonic acid release by vesicle assay


Bioorg Med Chem 15: 2883-91 (2007)


Article DOI: 10.1016/j.bmc.2007.02.016
BindingDB Entry DOI: 10.7270/Q24749JP
More data for this
Ligand-Target Pair