BDBM50206643 CHEMBL390480::N-(1-((2S,3R)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)butanoyl)piperidin-4-yl)-N-phenylpropionamide

SMILES CCC(=O)N(C1CCN(CC1)C(=O)[C@@H](N)[C@H](C)c1c(C)cc(O)cc1C)c1ccccc1

InChI Key InChIKey=PFMOTJNRKNDBQA-CLOONOSVSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50206643   

TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50206643(CHEMBL390480 | N-(1-((2S,3R)-2-amino-3-(4-hydroxy-...)
Affinity DataKi:  260nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptor transfected in HN9.10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50206643(CHEMBL390480 | N-(1-((2S,3R)-2-amino-3-(4-hydroxy-...)
Affinity DataKi:  300nMAssay Description:Displacement of [3H] DAMGO from rat mu opioid receptor transfected in HN9.10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50206643(CHEMBL390480 | N-(1-((2S,3R)-2-amino-3-(4-hydroxy-...)
Affinity DataIC50:  3.30E+3nMAssay Description:Antagonist activity at mu opioid receptor as inhibition of electrically stimulated guinea pig ileum contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed