BDBM50207482 CHEMBL223237::N-{4-[3-amino-1-(2-morpholin-4-yl-ethyl)-1H-indazol-4-yl]-phenyl}-N'-(3-methylphenyl)urea

SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2cccc3n(CCN4CCOCC4)nc(N)c23)c1

InChI Key InChIKey=IOEOFPWILLIIMB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50207482   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207482(CHEMBL223237 | N-{4-[3-amino-1-(2-morpholin-4-yl-e...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation in mouse 3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207482(CHEMBL223237 | N-{4-[3-amino-1-(2-morpholin-4-yl-e...)
Affinity DataIC50:  860nMAssay Description:Inhibition of FLT3 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed