BDBM50207485 CHEMBL220317::N-(4-(3-amino-1H-indazol-4-yl)phenyl)benzenesulfonamide::N-[4-(3-amino-1H-indazol-4-yl)phenyl]benzenesulfonamide

SMILES Nc1n[nH]c2cccc(-c3ccc(NS(=O)(=O)c4ccccc4)cc3)c12

InChI Key InChIKey=JEZDURDPMARJKQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50207485   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207485(CHEMBL220317 | N-(4-(3-amino-1H-indazol-4-yl)pheny...)
Affinity DataIC50:  1.12E+4nMAssay Description:Inhibition of c-Kit by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207485(CHEMBL220317 | N-(4-(3-amino-1H-indazol-4-yl)pheny...)
Affinity DataIC50:  1.12E+4nMAssay Description:Inhibition of c-Kit by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207485(CHEMBL220317 | N-(4-(3-amino-1H-indazol-4-yl)pheny...)
Affinity DataIC50:  4.62E+3nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation in mouse 3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed