BDBM50207489 1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-(2-fluorophenyl)urea::CHEMBL223583::N-[4-(3-amino-1H-indazol-4-yl)phenyl]-N'-(2-fluorophenyl)-urea

SMILES Nc1n[nH]c2cccc(-c3ccc(NC(=O)Nc4ccccc4F)cc3)c12

InChI Key InChIKey=VVCCQOIZUNRHOM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50207489   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207489(1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-(2-fluorop...)
Affinity DataIC50:  82nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation in mouse 3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50207489(1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-(2-fluorop...)
Affinity DataIC50:  34nMAssay Description:Inhibition of c-Kit by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207489(1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-(2-fluorop...)
Affinity DataIC50:  157nMAssay Description:Inhibition of FLT3 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50207489(1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-(2-fluorop...)
Affinity DataIC50:  34nMAssay Description:Inhibition of c-Kit by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed