BDBM50207818 CHEMBL3956725

SMILES NS(=O)(=O)c1ccc(SCc2ccc(cc2)C(F)(F)F)s1

InChI Key InChIKey=XRXMPNGFKACJMA-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50207818   

TargetCarbonic anhydrase 9(Homo sapiens (Human))
Riga Technical University

Curated by ChEMBL
LigandPNGBDBM50207818(CHEMBL3956725)
Affinity DataKi:  0.940nMAssay Description:Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase 9 preincubated for 10 mins prior to testing by stopped-flow CO2 hyd...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Riga Technical University

Curated by ChEMBL
LigandPNGBDBM50207818(CHEMBL3956725)
Affinity DataKi:  1.5nMAssay Description:Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase 12 preincubated for 10 mins prior to testing by stopped-flow CO2 hy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Riga Technical University

Curated by ChEMBL
LigandPNGBDBM50207818(CHEMBL3956725)
Affinity DataKi:  3.70nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 2 preincubated for 10 mins prior to testing by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Riga Technical University

Curated by ChEMBL
LigandPNGBDBM50207818(CHEMBL3956725)
Affinity DataKi:  4.25E+3nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 1 preincubated for 10 mins prior to testing by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed